Welcome to your new favorite weeknight dinner obsession: the **Easy Biscuit Pizza Casserole**! If your household, like ours, lives for pizza night – sometimes even twice a week! – then you’re constantly seeking fresh, fun ways to enjoy that beloved cheesy goodness. This casserole takes all the joy of a classic pizza and transforms it into an incredibly simple, baked dish using a pantry staple: canned biscuits. Get ready for a family-approved meal that comes together in about 40 minutes, delivering maximum flavor with minimal effort.

We’ve always been big fans of homemade pizza, experimenting with different crusts and toppings. The idea of “biscuit pizzas” sparked an instant wave of creativity, leading us to envision a hearty, comforting casserole. The result? A culinary revelation! This **Pizza Casserole with Biscuits** quickly earned its spot as a top contender for movie nights, game days, or any evening when you crave something incredibly delicious and satisfying without spending hours in the kitchen.
Imagine tender, fluffy biscuits, each generously stuffed with gooey mozzarella, zesty pizza sauce, and your favorite toppings, all baked together in one dish until golden brown and bubbly. It’s a complete meal that feels both indulgent and surprisingly straightforward to prepare. Get ready to ditch the takeout menu and dive into a homemade pizza experience that’s truly unique!

Why This Easy Biscuit Pizza Casserole Is a Must-Try
If you’re looking for compelling reasons to add this **Canned Biscuit Pizza Casserole** to your weekly rotation, look no further. It’s not just a meal; it’s a solution for busy evenings, picky eaters, and budget-conscious cooks!
- Lightning Fast & Family-Approved: This recipe is a true time-saver, clocking in at around 40 minutes from start to finish. Perfect for those chaotic weeknights when you need a delicious meal on the table without a fuss. Plus, who doesn’t love pizza? It’s a guaranteed hit with kids and adults alike, ensuring clean plates and happy faces.
- Endlessly Customizable: The beauty of this **Homemade Pizza Bake** lies in its versatility. You can tailor the toppings to suit every family member’s preference or accommodate various dietary needs. Whether you’re a fan of classic pepperoni, a veggie lover, or prefer a bold Hawaiian twist, this casserole is your canvas.
- Budget-Friendly Dinner Solution: Ditch the expensive pizza delivery! Making this **Quick Pizza Dish** at home is significantly cheaper than ordering out. Using readily available, affordable ingredients like canned biscuits, jarred sauce, and your choice of toppings means you get more bang for your buck, without compromising on flavor or satisfaction.
- So Easy, Even Kids Can Help: This is an excellent recipe for getting the whole family involved in the kitchen. Kids will love helping to stuff the biscuits with their favorite fillings, making it a fun and interactive cooking experience. It’s a fantastic way to introduce them to basic cooking skills in an enjoyable setting.
- Comfort Food at Its Best: There’s something inherently comforting about a warm, cheesy casserole. This **Stuffed Biscuit Pizza** delivers that ultimate comfort food experience, making it perfect for chilly evenings, cozy movie nights, or whenever you need a little culinary hug.
Essential Ingredients for Your Pizza Casserole
Gathering the right ingredients is the first step to creating this delicious **Biscuit Pizza Casserole**. The beauty of this recipe is that most components are simple, affordable, and likely already in your pantry or easily found at any grocery store.

- Biscuits: The undisputed star of this **Canned Biscuit Pizza**! For best results, we highly recommend using large, flaky canned biscuits like Pillsbury Grands! Southern Homestyle. Their substantial size and tender texture make them perfect for slicing open and stuffing, creating individual “pizza pockets” that puff up beautifully during baking. Don’t go for the smaller varieties, as they can be challenging to fill.
- Pizza Sauce: A good quality pizza sauce is crucial for that authentic flavor. While we often rely on a favorite jarred pizza sauce for convenience – keeping it on hand for quick meals – if you have homemade pizza sauce, it will elevate this recipe to an even more gourmet level. Marinara sauce can also work in a pinch, just ensure it has a robust flavor.
- Cheese: We double up on the cheese for ultimate gooeyness! You’ll need fresh mozzarella, ideally pre-sliced, to tuck inside each biscuit for a wonderfully soft, melting center. Additionally, shredded mozzarella is sprinkled over the top of the casserole to create a golden, bubbly crust that everyone craves. Feel free to experiment with a blend of mozzarella and provolone for added depth.
- Garlic Butter: This simple yet powerful addition is what truly sets this casserole apart. A mixture of melted butter, fresh minced garlic, and a touch of fresh parsley brushed over the biscuits before baking adds an incredible aroma and savory depth. It helps the biscuits achieve a beautiful golden brown while infusing them with rich flavor.
- Toppings: We opted for classic pepperoni in our version, a universal favorite that perfectly complements the cheesy biscuits. However, this is where you can let your creativity shine! Think beyond pepperoni – a “supreme” version with bell peppers, onions, and mushrooms, or even a “Hawaiian” with ham and pineapple would be absolutely amazing. See our “Variations” section for more ideas!
Step-by-Step Guide to Making Biscuit Pizza Casserole
Crafting this **Easy Pizza Casserole** is straightforward, making it perfect for novice cooks or busy weeknights. Follow these simple steps to bring this comforting dish to life:
- Prepare Your Workspace and Preheat Oven: Start by preheating your oven to 375°F (190°C). This ensures your oven is ready for baking as soon as your casserole is assembled. Lightly grease a 10-inch oven-safe pan or casserole dish.
- Slice and Stuff the Biscuits: Carefully open your cans of jumbo biscuits and separate each one. Using a sharp knife, make a horizontal cut halfway through the middle of each biscuit to create a pocket. Be careful not to cut all the way through. Inside each pocket, place a slice of fresh mozzarella cheese, a couple of pepperoni slices (or your chosen topping), and a small spoonful of pizza sauce. Don’t overfill, or they might burst.
- Arrange in Casserole Dish: Once stuffed, arrange the pizza biscuits snugly in your prepared casserole dish, placing them open-side up. They should fit together like a puzzle, creating a cohesive casserole. The close arrangement helps them bake evenly and form that delicious casserole texture.
- Prepare and Apply Garlic Butter: In a small, microwave-safe bowl, melt the butter. Stir in the minced garlic and fresh parsley until well combined. Using a pastry brush, generously brush this aromatic garlic butter mixture over the tops of all the stuffed biscuits. This step is crucial for adding flavor and helping the biscuits achieve a beautiful golden-brown crust.
- Top with Shredded Cheese: Evenly sprinkle the shredded mozzarella cheese over the entire casserole, ensuring all the biscuits are covered. This creates an irresistible, bubbly, cheesy layer on top.
- Bake to Golden Perfection: Place the casserole in the preheated oven and bake for 35-40 minutes. The baking time may vary slightly depending on your oven and the thickness of your biscuits. You’ll know it’s ready when the biscuits are puffed up, golden brown on top, and the cheese is melted, bubbly, and slightly caramelized at the edges.
- Serve and Enjoy: Carefully remove the casserole from the oven and let it cool for a few minutes before serving. This allows the cheese and sauce to set slightly. Serve immediately, perhaps with an extra side of warm pizza sauce for dipping. Enjoy your homemade **Biscuit Pizza Casserole**!
Expert Tips for the Best Biscuit Pizza Casserole
To ensure your **Pizza Casserole with Biscuits** turns out perfectly every time, keep these helpful tips in mind:
- Biscuit Size Matters: Always opt for “big” or “jumbo” sized canned biscuits, like Pillsbury Grands!. Smaller biscuits are much harder to stuff without tearing and won’t give you the same fluffy texture in a casserole.
- Pre-Slice for Convenience: For a true shortcut, look for pre-sliced fresh mozzarella. This saves time and ensures uniform cheese distribution inside each biscuit. If you can’t find it, slicing a block of fresh mozzarella yourself is easy.
- Don’t Overstuff: While it’s tempting to load up on toppings, overstuffing the biscuits can lead to them falling apart during baking or becoming soggy. A slice of cheese, a couple of pepperoni slices, and a small spoonful of sauce are usually enough.
- Customize Your Casserole Dish: To make a smaller batch for fewer servings, simply halve the ingredients and use a deep pie plate or a smaller oven-safe dish. Ensure the biscuits fit snugly to create a cohesive casserole effect.
- Prevent a Soggy Bottom: If you’re concerned about a soggy bottom, you can lightly pre-bake the empty biscuit pockets for about 5-7 minutes before stuffing them. Alternatively, ensure your pizza sauce isn’t too watery, or use slightly less sauce inside each biscuit.
- Make Ahead Option: You can assemble the casserole (stuff biscuits, arrange in dish, brush with garlic butter, and sprinkle with cheese) up to a few hours in advance. Cover it tightly with plastic wrap and refrigerate. Add an extra 5-10 minutes to the baking time if baking from cold.
- Storage and Reheating: Leftovers can be stored in an airtight container in the refrigerator for 2-3 days. Reheat individual portions in the microwave or oven until warmed through. The biscuits may lose a little crispness but will still be delicious.

Delicious Variations to Explore
One of the best things about this **Biscuit Pizza Casserole** is its incredible adaptability. Once you master the basic recipe, you can easily switch up the toppings and flavors to create an entirely new dish. Here are some inspiring ideas to get you started:
- Vegetarian Delight: Load up on colorful vegetables! Think diced bell peppers (red, green, yellow), thinly sliced red onion, sautéed mushrooms, black olives, or even a handful of fresh spinach or sun-dried tomatoes.
- Meat Lover’s Dream: Beyond pepperoni, consider cooked and crumbled Italian sausage, crispy bacon bits, diced ham, or seasoned ground beef. Ensure any meat toppings are pre-cooked to prevent a soggy casserole.
- Hawaiian Twist: For those who love sweet and savory, stuff the biscuits with diced ham and small pieces of pineapple. A sprinkle of red pepper flakes can add a nice little kick.
- BBQ Chicken Pizza Casserole: Shredded cooked chicken tossed in your favorite BBQ sauce, combined with thinly sliced red onion and a sprinkle of fresh cilantro after baking, makes for a smoky, flavorful variation. You might swap out some of the mozzarella for a cheddar blend here.
- Buffalo Chicken Kick: Mix shredded cooked chicken with buffalo sauce and a touch of ranch or blue cheese dressing. Stuff into biscuits and top with mozzarella, perhaps some blue cheese crumbles if you’re a fan.
- Breakfast Pizza Casserole: A fantastic idea for brunch! Fill biscuits with cooked breakfast sausage, scrambled eggs, and a blend of cheddar and mozzarella cheese. Skip the pizza sauce or use a white gravy as the base.
- White Pizza Casserole: Instead of red pizza sauce, use a creamy garlic Alfredo sauce or a ricotta cheese mixture seasoned with garlic and herbs. Top with mozzarella and perhaps some fresh basil.
What to Serve with Your Pizza Casserole
While the **Easy Biscuit Pizza Casserole** is a hearty and complete meal on its own, pairing it with a simple side can elevate the dining experience. Here are some serving suggestions:
- Fresh Green Salad: A crisp, light green salad with a vinaigrette dressing is the perfect counterpoint to the rich and cheesy casserole.
- Garlic Bread or Breadsticks: If you’re a carb enthusiast (and who isn’t when pizza is involved?), extra garlic bread or warm breadsticks are always a welcome addition for soaking up any extra sauce.
- Extra Dipping Sauce: Provide a bowl of warm marinara sauce for dipping, or even ranch dressing for those who enjoy a creamy complement to their pizza.
- Steamed Vegetables: A simple side of steamed broccoli, green beans, or asparagus adds a healthy touch without overpowering the main dish.
More Pizza-Inspired Creations
Can’t get enough pizza? Explore these other fantastic recipes that celebrate the joy of pizza in various forms:
- Easy NYC Pizza Dough
- Campfire Pizza Nachos
- BBQ Pulled Pork & Pineapple Pizza
Discover More Comforting Casseroles
If you love the ease and satisfaction of a good casserole, be sure to check out these other comforting recipes:
- Chicken Cordon Bleu Casserole
- Instant Pot Twice Baked Potato Casserole
- Sausage Egg McMuffin Casserole
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Biscuit Pizza Casserole
Print Recipe

Ingredients
- 2 (8 count) Cans of Grands Southern Homestyle Biscuits
- 8 oz Fresh Sliced Mozzarella Cheese
- 20 Slices of Pepperoni
- 1/2 Cup Pizza Sauce
- 1 Tbsp Parsley
- 3 Tbsp Salted Butter
- 3 Cloves Garlic, minced
- 1/2 Cup Shredded Mozzarella
Instructions
- Preheat the oven to 375° F.
- Open and separate biscuits. Cut into the middle of each biscuit to form a pocket. Stuff with one slice of mozzarella cheese, a couple slices of pepperoni, and a spoonful of sauce. Place each biscuit open side up into a 10″ oven-safe pan or casserole dish.
- Melt butter, stir in garlic and parsley. Brush bread generously with butter mixture. Sprinkle shredded mozzarella over the top.
- Place in the oven for 35-40 minutes, until cheese has melted and the biscuit tops are beginning to brown.
- Serve immediately with extra pizza sauce for dipping, if desired. Enjoy!
